Special precautions

Fingolimod for multiple sclerosis and emerging indications: appropriate patient selection, safety precautions, and special considerations

Fingolimod (FTY720), an immunotherapeutic drug targeting the sphingosine-1-phosphate receptor, is a widely used medication for relapsing-remitting multiple sclerosis (MS). Apart from the pivotal Phase III trials demonstrating efficacy against placebo and interferon-β-1a once weekly, sufficient clinical data are now available to assess its real-world efficacy and safety profile. Approved indicat...

New Hypoglycemic Agents Require Perioperative Precautions New Hypoglycemic Agents: A Special Presentation

Background: New noninsulin hypoglycemic agents, the incretin and amylin groups, are available to treat patients with type 2 diabetes and inadequate glucose control with the regular routinely used agents, namely metformin or sulfonylurea. Incretin therapies are based on the release of intestinal peptides (glucagon-like peptide 1) in the presence of glucose in the gut which stimulates insulin sec...

Obligatory precautions against infection.

If we have a duty not to infect others, how far does it go? This question is often discussed with respect to HIV transmission, but reflection on other diseases like influenza raises a number of interesting theoretical issues. I argue that a duty to avoid infection not only yields requirements for persons who know they carry a disease, but also for persons who know they are at increased risk, an...

Air-raid Precautions

Air Raid Precautions